Originally from Boyle Heights in East Los Angeles, Agüero-Esparza was exposed to the potential and richness of materials and the love of the hand-made working in her parents' shoe shop. She received a BA in Art from the University of California Santa Cruz, and MFA from San Jose State University. Agüero-Esparza has been an active artist, arts educator and arts administrator in the Bay Area exhibiting her work in numerous institutions including the San Jose Museum of Art, Triton Museum, Yerba Buena Center for the Arts, The Santa Cruz Museum, MACLA, Palo Alto Arts Center, Galeria de la Raza, and the De Young Museum. In 2017, her work was featured in the exhibition The U.S.-Mexico Border: Place, Imagination, and Possibility at the Craft Contemporary Museum, Los Angeles as part of the Getty Foundation Southern California initiative Pacific Standard Time: LA/LA, an ambitious exploration of Latin American and Latino art. In 2019, the U.S.-Mexico Border exhibition traveled to Lille, France as part of the Eldorado Lille3000 arts festival. Sponsored by festival organizers, Agüero-Esparza traveled to France and worked with community members teaching huarache-making workshops at the Maison Folie Wazemmes.